Nene Nanakorobi, a cheerful full-body cyborg who yearns for global harmony, crosses paths with inventor Uzal Delilah aboard a cruise ship bound for the picturesque Cenancle Island. They quickly bond, along with Clarion, a feline combat android serving as Uzal’s pet. However, their budding friendship is tested when terrorists strike the island. To protect Uzal, Nene is gifted the Pandora Device extracted from Clarion, granting her the power to instantly master advanced abilities, though Uzal appears to perish in the process. Now, the duo embarks on missions ranging from rescuing children from mall fires to apprehending criminals, all in pursuit of world peace. Their journey is complicated by B.U.E.R, a sentient laser disguised as a distorted teddy bear whose lewd behavior and volatile power endanger their safety. Compounding the trouble, the brilliant inventor Takumi Korobase, who serves as Nene’s guardian, is obsessed with acquiring B.U.E.R. As Nene and Clarion struggle to safeguard the device from malicious forces while pursuing their utopian ideals, the immense pressure threatens to tear their newfound bond apart.