In a world where ayakashi, mysterious and often imperceptible supernatural entities, coexist with humans, certain ayakashi pose a threat by draining human life force. Exorcist ninjas, like those from the esteemed Kazamaki clan, are dedicated to defending humanity against these malevolent spirits.
Matsuri Kazamaki, a young exorcist ninja, and Suzu Kanade, his childhood friend and an ayakashi medium with extraordinary vitality that attracts ayakashi, face conflicting perspectives. Matsuri sees ayakashi as inherently dangerous and aims to shield Suzu from them, while Suzu yearns to remain connected to the ayakashi. Their relationship is tested when they encounter Shirogane, the formidable "King of Ayakashi," intent on consuming Suzu. In a desperate attempt to save her, Matsuri successfully seals Shirogane’s powers, but not before the ayakashi retaliates by transforming Matsuri into a girl.
As Matsuri navigates his new feminine form and continues to battle hostile ayakashi, the dynamics of his relationship with Suzu become more complicated. Suzu's feelings towards Matsuri become uncertain, adding another layer of confusion to their already strained bond.