Kusuo Saiki views his psychic abilities as a curse rather than a blessing. Possessing powers like telepathy and x-ray vision, he merely wishes to lead a mundane, tranquil existence, free from the complications his talents create. Despite his best efforts to conceal his supernatural gifts from those around him, Saiki continually attracts the attention of eccentric individuals, such as the dim-witted Riki Nendou and the paranoid Shun Kaidou. While battling this relentless chaos, Saiki realizes that securing the ordinary life he desperately desires is far more difficult than he ever anticipated.