Fifteen years after the catastrophic Second Impact, humanity is under siege from colossal angelic beings known as Angels, who attack Tokyo-3 one after another. Despite deploying their most advanced weapons and military strategies, mankind is powerless against them. The only hope lies with NERV, a secretive organization led by the cold-hearted Gendou Ikari. NERV operates giant humanoid robots called Evangelions, equipped with cutting-edge weaponry and protective barriers called Absolute Terror Fields, to fight the Angels.
After years of abandonment by his father, 14-year-old Shinji Ikari returns to Tokyo-3. He constantly struggles with deep-seated trauma from losing his mother and the emotional neglect from his father. Afraid to form connections, Shinji's life changes when he meets 29-year-old Misato Katsuragi, a high-ranking NERV officer who offers him the maternal warmth he has never known.
A sudden Angel attack forces Shinji into action, revealing Gendou's true reason for summoning him: Shinji is the only one who can effectively pilot Evangelion Unit-01, a new robot that syncs with his biological signals. Despite the severe psychological torment of piloting an Evangelion, Shinji defends Tokyo-3 from the angelic threat, unaware of his father's dark schemes.