Anime Like Resident Evil: Death Island

Parasitic aliens suddenly descend upon Earth, infiltrating humanity by burrowing into the brains of vulnerable targets. These insatiable creatures seize complete control of their hosts and can morph into various forms to hunt unsuspecting prey. Sixteen-year-old high school student Shinichi Izumi is attacked by one of these parasites, but it fails to take over his brain, ending up in his right hand instead. Unable to move to its intended location, the parasite, named Migi, must rely on Shinichi to survive. This forces the duo into an uneasy coexistence as they defend themselves against hostile parasites determined to eliminate this new threat to their kind.

In 1988, a boy wielding psychic abilities triggers a catastrophic explosion in Tokyo that sparks World War III. To avert further devastation, he is detained and disappears from public knowledge. Three decades later, the rebuilt Neo-Tokyo is plagued by gang warfare and anti-government terrorism. Shoutarou Kaneda commands "the Capsules," a crew of delinquents famous for their oversized custom bikes and ongoing feud with their rivals, "the Clowns." During a clash with these rivals, Kaneda’s best friend, Tetsuo Shima, collides with an esper who has fled a government facility. This incident awakens latent, dangerous powers within Tetsuo. As the authorities move to contain this new psychic threat before it can destroy the city once more, Tetsuo’s escalating abilities place him at the center of the chaos.

After giving his life to rescue a homeless man from a speeding train, Kei Kurono regains consciousness in a peculiar room alongside several other freshly dead individuals and a mysterious black orb. While they attempt to make sense of their situation, the sphere unveils a collection of weapons and black bodysuits, then orders them to eliminate an alien before teleporting them to an unfamiliar destination. With few explanations, Kei teams up with his childhood friend Masaru Katou and an unnamed woman. As they explore their surroundings, they soon understand that they have entered a grim and treacherous realm filled with constant threats.

As the comforting warmth of daylight fades, ethereally beautiful beings become the unchallenged rulers of the night, striking terror into all living things. Water freezes solid at the approach of these blood-drinking monsters, and their victims recognize that this eerie cold signals their unavoidable end. Fortunately, the vampire population is shrinking, thanks to the fearless bounty hunters who pursue and destroy these nearly immortal predators. One night, tragedy strikes the Elbourne family when their daughter Charlotte is taken by Meier Link, a highly respected vampire lord protected by a horde of monsters. To rescue their beloved Charlotte, the family enlists the Marcus Brothers, a ruthless crew of vampire hunters, and D, a sword-wielding dhampir—a half-vampire, half-human possessing the strengths of both kinds and the weaknesses of neither. The hunters rush to save Charlotte, but if her captor decides to make her a vampire, they must kill her. Furthermore, their mission must succeed before Meier reaches the impenetrable vampire castle of Carmilla and takes Charlotte beyond humanity's grasp forever.

In the 21st century, humanity dispatched algae and cockroaches to Mars with the intention of terraforming the planet, as these species could withstand its harsh conditions. What was not foreseen was their extraordinary capacity for adaptation. By the 26th century, a lethal illness called the Alien Engine Virus is devastating Earth, with its potential cure believed to exist only on Mars. The problem is that Mars is now overrun by the "Terraformars"—highly intelligent, powerful humanoid cockroaches that mutated from the original specimens sent there. The Annex I team, composed of one hundred men and women who have undergone genetic enhancement with traits from formidable Earth organisms, has been dispatched to Mars on a mission to uncover the source of the Alien Engine Virus and aid in humanity's salvation, marking the beginning of the crew's desperate struggle for survival.

Immortality is something many people might wish for. But would they still desire it if they knew it would subject them to endless attacks? That is the reality for Rin Asougi, an immortal private investigator—there is no shortage of individuals who want her dead. Over the centuries, she has met countless gruesome ends, only to return to life each time as if nothing happened. In 1990, while searching for a lost cat, Rin encounters Kouki Maeno, a man who believes his memories are faulty. Agreeing to assist him, Rin soon discovers that Kouki is not what he appears to be, all while moving closer to her true enemy. This foe knows Rin and her kind all too well, and if she dies by his hand, she may stay dead forever.

Even though Kei Kurono, Masaru Katou, and Kei Kishimoto thought they had returned to their ordinary lives, they are pulled back into the deadly game due to Gantz's renewed activity. The black sphere keeps summoning people who have recently died to fight alien invaders. And because they survived the previous two encounters, the trio is far more ready for the missions ahead. As they advance through the tournament's stages, the three continue their effort to earn 100 points, which is believed to be the only way to permanently leave the parallel dimension. However, with the relentless assault of alien invaders and the constant danger of death, they must first concentrate on the immediate task: staying alive.

The narrative begins with a confrontation between two opposing heroes, ZET and ALPHAS, before delving into their backstories—Jin Kanzaki, a youth possessing the power to become the superhuman entity called ZET, and Kouga Amagi, a young man driven by a powerful sense of justice who employs technology to battle as ALPHAS. The destinies of these two individuals and the people connected to them become intertwined as they struggle to safeguard humanity and eliminate monstrous horrors referred to as Players.

Two years after the catastrophic tsunami that struck Japan, police officer Kiyomasa Senji strives to make the world a safer place. Utilizing his Branch of Sin powers, he stops criminals by any means necessary. After rescuing a boy named Izuru Tsukiyoshi from the gang Goreless Peace, the conflict between Kiyomasa and his enemies escalates rapidly, reaching an explosive intensity. Offering a glimpse into the past of the future Deadman, the story follows Senji, further developing the reasoning that drives his actions later in life.

Ten millennia into the future, the world has transformed into a vastly different realm; creatures of nightmare wander freely, and humanity, despite possessing advanced technology and cybernetic steeds, lives a rustic existence more reminiscent of bygone eras. The narrative centers on a small village suffering from relentless monster assaults and living under the oppressive reign of Count Magnus Lee, a formidable vampire lord who has dominated the land for millennia. When a young woman is bitten by the Count and selected as his latest prize, she seeks aid from a quiet, enigmatic drifter named D. As it turns out, D is among the finest vampire hunters in existence, and he takes it upon himself to carve through Magnus Lee's numerous servants and bring an end to the Count's dominion.

Death does not have to be final; resurrection is possible, but only by conquering the challenge set by the mysterious black sphere known as Gantz. On his way home to celebrate his younger brother's birthday, the courageous and kind-hearted student Masaru Katou is fatally stabbed. He regains consciousness in a small room overlooking Tokyo's skyline—and finds others there as well. To his surprise, this is no afterlife; it is a waiting room for a deadly game where their lives are at stake. Before Masaru can fully grasp what is happening, he receives a gun and is instantly transported to the center of Osaka with a single directive: eliminate any alien on sight. Together with the elderly Yoshikazu Suzuki, the gorgeous idol Reika Shimohira, and the cold yet seasoned Jouichirou Nishi, Masaru must conquer his fears to survive the game and return home to his waiting brother.

During the twelfth century, the swordsman Kurou flees terrifying pursuers into a dense forest with his attendant Benkei. They discover the hidden residence of the enigmatic and stunning Kuromitsu, who welcomes them but strictly forbids them from entering her private chambers. Compelled by curiosity and perhaps a doomed affection, Kurou looks inside and discovers Kuromitsu consuming the blood of deceased men. Realizing she is an immortal vampire, he vows to stay by her side, even turning into a vampire himself to remain with her forever. Yet, the secretive Red Army recruits Benkei, who betrays Kurou and decapitates him. Centuries later, Kurou awakens in a ruined, futuristic Japan and embarks on a quest to find his beloved and take vengeance on the Red Army.

In Terra Formars: Revenge, the crew of Annex I persist in their war against the Terraformars, massive humanoid cockroaches that evolved from specimens sent to Mars long ago. Instead of finding a remedy for the devastating Alien Engine Virus ravaging Earth, the Annex I team discovers that various squadrons harbor their own nationalistic agendas. Consequently, the fighters must contend not only with the Terraformars to stay alive but also with one another in a ceaseless struggle for global supremacy.

A lethal virus called Medousa spreads worldwide, petrifying humans with no cure, pushing civilization to the brink of collapse. The only salvation lies in Venus Gate Corporation's radical initiative: placing 160 individuals into cryogenic sleep for up to a century, until a remedy emerges. Kasumi Ishiki is among the lucky chosen ones, but she dreads being parted from her twin sister, Shizuku; still, the girls cling to hope of reuniting in the future. Yet when Kasumi awakens, reality defies her expectations. The cryo-facility is overgrown with thorns, and bizarre monsters attack the survivors. Most of the awakened perish in the ensuing chaos, but Kasumi and a handful of others navigate the labyrinthine complex, seeking to uncover the truth behind Medousa and the hidden motives of Venus Gate Corporation.

In 2030, Japan has been entirely consumed by a viral outbreak called "Gibia," which transforms those infected into a variety of monsters depending on their age, gender, and ethnicity. A samurai and a ninja from the early Edo period are transported through time to a devastated Japan, where they join a professor who is searching for a cure to the virus. As a team, they battle countless Gibia creatures, criminals, and other dangerous enemies on their quest to rescue humanity.

Several months after a probe returning from Mars disintegrates during reentry, mysterious creatures known as "Ancients" start emerging across Tokyo. These aggressive and hazardous beings cannot be eliminated by conventional weapons. While researchers struggle to determine the reason for their sudden emergence, the monsters cause widespread destruction globally. Humanity discovers hope with the MARS suit—a new weapon designed to combat these foes. However, the suit can only be operated by individuals possessing specific DNA. Enter Takeru Hinata, a typical teenager with a difficult history and one of the few capable of piloting the sole weapon effective against the Ancients. Assisted by the AAST, a specialized police force formed to combat the dangerous creatures, the young man fights against both personal and worldwide demons while attempting to uncover the true origin of Earth's new threats.

In the autumn of 2005, a year after the events of the Resident Evil 4 game, zombies unexpectedly emerge at a United States airport for reasons that remain unexplained. This sudden appearance of the undead triggers a potential outbreak, plunging the area into danger.

Adaptation of the Bugs 2 arc of the manga.

When he was young, Yuu Kusaka made a wish on a shooting star to fight for justice and protect the helpless. After one of his friends died, however, he lost the drive to honor that promise. Instead of using his mysterious ability to aid those in need, he exploits it to earn money, ignoring the suffering around him. His self-serving life continues until he is forced to fight for survival against another classmate with similar powers. He is rescued by Eimu Yoake, a mysterious girl who also possesses strange abilities. Eimu reveals that his power comes from an Ayakashi—a parasitic creature that grants the host special abilities while gradually draining their life energy. She assists him in fully awakening his own Ayakashi. Now aware of the being inside him, Yuu must live up to his childhood oath by using his Ayakashi to protect others and fight those who employ their own for evil, all while uncovering the truth behind his friend's death.

American special agent Leon S. Kennedy covertly enters a small Eastern European nation to investigate reports that Bio Organic Weapons (B.O.W.s) are being employed in warfare. Shortly after his infiltration, the U.S. government commands him to depart at once. Resolved to find the truth, Leon disobeys the order and proceeds into the combat zone to put a stop to the series of tragedies resulting from the B.O.W.s.

Sho Fukamachi, an ordinary teenager, stumbled upon an alien object called the Unit, forever altering his existence. The Unit bonded with Sho, transforming him into an immensely powerful life-form known as Guyver. Armed with this extraordinary strength, Sho fights against the enigmatic Chronos organization and its Zoanoids, striving to safeguard his friends and his world. Unbeknownst to Sho, his struggle against Chronos will ultimately unveil the origins of humanity, humanity's fate, and the Creators.

To prevent a vengeful arms dealer from unleashing a deadly virus across New York, Chris Redfield recruits Leon S. Kennedy and Rebecca Chambers for help.

Colin MacLeod, an immortal Highlander from Scotland, journeys alongside the witty ghost Amergan as he pursues Marcus Octavius, an immortal tyrant who murdered Colin's lover on the Celtic plains hundreds of years ago. The former metropolis of New York now lies submerged beneath the water, leaving only one imposing fortress rising above the waves—the stronghold of Marcus Octavius. MacLeod finds himself divided between rescuing the remaining inhabitants of New York and tracking down his sworn enemy.

Federal Agent Leon S. Kennedy teams up with TerraSave staff member Claire Redfield to investigate a zombie outbreak.