Best Mystery Anime of 2025

Leveraging her sharp intellect and extensive understanding of pharmacology and toxins, Maomao was instrumental in unraveling the mysteries and conspiracies that plagued the imperial court. After coming to terms with the truths regarding her parents, she resumes her regular responsibilities serving the emperor’s top consorts. In addition, she collaborates with the eunuch Jinshi to improve the lives of the ladies-in-waiting, assisting them in learning how to read. Yet, the arrival of a merchant caravan brings fresh intrigue. A series of suspicious coincidences involving the travelers and their goods disturbs Maomao, prompting her to probe the enigmatic events surrounding the convoy. As threats from both external and internal sources jeopardize the equilibrium among the imperial concubines, Maomao relies on her cleverness and medical knowledge to protect the women from danger.

Six months have passed since Yoshiki Tsujinaka’s best friend, Hikaru Indou, vanished into the mountains and returned a week later with no memory of the event. Sensing that the returning Hikaru is not the person he knows, Yoshiki confronts him, prompting the entity to reveal its true monstrous form and plead for silence to avoid killing Yoshiki. Despite being paranormal, the imposter displays a childlike innocence and eagerness to experience human sensations, such as the summer heat and rural life. For Yoshiki, whose grief drives him to cling desperately to his friend, it hardly matters if this Hikaru is a fake built on stolen memories, provided he never leaves again. As their bond deepens, it becomes increasingly evident that a dangerous supernatural force has descended from the mountains into their village.

In a steam-powered Victorian era filled with dreadnoughts and occult terrors, Zhou Mingrui finds himself reborn as Klein Moretti. He treads a precarious line between light and shadow, caught up in the conflicts of warring Churches. This is the tale of boundless potential...and unimaginable peril.

With its flickering streetlights, moldy back alleys, and bustling inhabitants, the Second Kowloon Walled City—despite the decay of its already-demolished predecessor—evokes a unique nostalgia that its residents find charming. Within the confines of this fading yet cherished environment lives Reiko Kujirai, a 32-year-old real estate agent deeply in love with her colleague, Hajime Kudou, who is two years younger. Although they have their disagreements, the two get along well enough to share the pleasures of the walled city together. But everything begins to unravel when Kudou, half-asleep, suddenly kisses Kujirai—apparently returning the feelings she has not yet confessed. However, when Kudou explains that he mistook her for someone else, Kujirai is drawn into a chain of events that lead her to a past she cannot recall.

In a future where children are scarce and treated as Japan's most precious resources, Christmas has become nothing more than a forgotten legend. At Daikoku Welfare Academy—a boarding school where students are educated, protected, and monitored—the mythical figure of Santa Claus is dismissed as fictional by the children. Adults, however, regard Santa Claus as a very real threat that must be eliminated by the Saint Nick Pursuit Unit should he ever appear. Shiori Fuyumura, a student at Daikoku Welfare Academy, is desperate to locate her best friend Ichie Ono, who was declared dead after vanishing six months earlier. One morning, Fuyumura summons her fellow class representative Kazushige Sanda and immediately attacks the unsuspecting boy. She believes Sanda is the descendant of the infamous Santa Claus—the only person capable of granting her wish to find Ono—and is resolved to awaken his hidden true self by any means necessary.

Perched on the roof of Tenikai General Hospital lies the unorthodox Department of Investigative Pathology, led by the peculiar Dr. Takao Ameku. This small unit, made up of Takao and her only staff member Yuu "Kotori" Takanashi, handles intricate medical puzzles that elude other hospital divisions. Takao, obsessed with mysteries, frequently inserts herself into intriguing cases, often annoying both her coworkers and law enforcement. Despite the trouble her interference causes for the hospital and others, no one can dispute her sharp intellect as she constructs diagnoses. Regardless of the medical field involved, Takao and the somewhat hesitant Takanashi are capable of solving any case.

Queen Victoria of England has tasked her loyal watchdog, 13-year-old Earl Ciel Phantomhive, with investigating a string of suspicious deaths in southern Germany. In several villages, every victim shared a single detail: they had entered the Werewolves' Forest just before developing strange deformities and dying. Local rumors attribute these tragedies to a "witch's curse," a belief deeply rooted in old folklore among the nearby villagers. Skeptical of any true supernatural involvement, Ciel and his contracted demonic butler, Sebastian Michaelis, along with the rest of the Phantomhive servants, discover an isolated village within the Werewolves' Forest. The settlement is inhabited exclusively by women who are hostile toward outsiders and serve a young girl with emerald eyes and bound feet, Sieglinde "Green Witch" Sullivan. While Ciel and Sebastian search for the truth, they soon become victims of the curse themselves, revealing that the local legends may hold more reality than initially apparent.

First-year student Takahiko Urino wants to write something truly unique for the school newspaper, Furnado Monthly. With encouragement from his girlfriend, Yuki Osanai—an apparently ordinary second-year student—Urino convinces the newspaper club to let him pursue an unusual story. A series of small-scale fires has escalated into serial arson, and Urino aims to predict where future fires will occur and identify the perpetrator. However, his fixation on the case does not always reflect well on the club, and Osanai may not be so pleased with her boyfriend's increasing arrogance. Meanwhile, another supposedly unremarkable student, Jougorou Kobato, spends quiet days with his girlfriend, Tokiko Nakamaru. But when he witnesses a fire connected to a past case and involving Osanai herself, Kobato cannot help but revert to his former, less-than-ordinary ways as he seeks the truth.

In the world of detectives, Keiichirou Nagumo is a well-known figure. During his high school years, he was hailed as a prodigy for solving difficult cases that even the police couldn't handle. But according to rumors, those days are behind him. Then one day, an unexpected visitor bursts into his office: Mashiro, an energetic high school student who insists on being hired as his new assistant. Keiichirou tries to dismiss her, but Mashiro refuses to give up. Determined to become a detective, she starts proving her worth by introducing him to the latest technology and offering a fresh approach to his work. So Keiichirou agrees to take her on as his assistant, beginning a new chapter in his career—one where he is constantly caught off guard by the modern breed of detectives.

In a different version of 2023, the Your Forma—a revolutionary "smart thread" technology originally created to combat a massive viral encephalitis outbreak—has become essential to everyday life. However, these convenient devices have a hidden cost: they capture every image, sound, and even emotion their users experience. For electronic investigator Echika Hieda, exploring people's memories through the Your Forma to gather evidence for solving the most challenging crimes is routine. The issue is that she is so proficient at her job that her partners' brains literally overheat trying to match her pace. After sending too many assistants to the hospital, the higher-ups finally provide Echika with a partner of equal capability: a highly intelligent but impudent android named Harold Lucraft. Can this mismatched pair overcome their mutual distrust and stop a dangerous technological plague from spreading globally before time runs out?

Set in an eternal twilight, the Tasogare Hotel serves as a limbo for souls suspended between life and death. Unaware of their ultimate fate, guests are tasked with recovering forgotten memories using mementos concealed in their assigned rooms. While most patrons move on or return to the living world within a few days, a select few remain at the establishment for unusually long periods. Neko Tsukahara, a young woman with a stoic expression, arrives at this peculiar hotel. Guided by the staff, she gradually recovers her own memories and becomes deeply engaged with the struggles of her fellow guests. Finding the resolution of their affairs and the hotel's underlying mysteries too compelling to ignore, Neko determines that merely being a guest is insufficient to quench her curiosity.

Reiko Houshou, the heir to a vast corporate empire, appears to be just another wealthy young woman. But in truth, she works as a rookie detective for the Kunitachi Police Department, a fact she keeps hidden from her incompetent boss, Kyouichirou Kazamatsuri—the flashy heir to his family's motor business. While investigating a case involving her college friends, Reiko struggles to determine both the culprit and their motive. Then, out of nowhere, a man named Kageyama approaches her, introducing himself as her newly assigned butler. As soon as Reiko shares her concerns with him, he scolds her for lacking deductive skills and promptly helps her solve the case. With the sharp-tongued Kageyama by her side, Reiko may finally become the detective she aspires to be.

University students Kuriaki Magi and Yaeko Kirihara see a man get struck fatally in the head, but they can hardly believe it when he runs away without a scratch. Catching up to him, they learn the man, Momoyuki Mogura, is immortal. At first Magi and Yaeko assume Mogura is mistaken, but their perspective changes when they start noticing apparitions. Mogura explains that these are spirits of the dead that generate demon fire—a light that directs souls after death. Deprived of the right to carry that fire, Mogura has spent years collecting spirit byproducts, hoping one day to enter the afterlife. With Magi and Yaeko now assisting him in tracking down more spirits, the enigmatic Mogura might finally achieve his strange goal.

For the highly learned scholar Akihiko Chuuzenji, every enigma in the world can be unraveled through cold logic. After taking a position as a Japanese teacher at Tokyo Metropolitan Mitogawa High School, he crosses paths with Kanna Kusakabe, a cheerful young girl whose eagerness to assist others frequently gets her into trouble. When Kanna learns that a classmate is supposedly cursed to death by a ghost, she decides to explore the school building at night—only to discover that the so-called ghost is actually Akihiko. Unwilling to reveal the hidden room packed with forbidden books where he works to the other students, Akihiko opts to start a rumor that Kanna single-handedly exorcised the ghost. Much to Kanna's dismay, her peers now consider her an occult expert and force her to look into several seemingly paranormal incidents. However, she can count on the assistance of her teacher Akihiko, who—despite his prickly personality—is resolved to prove that reason always triumphs over superstition.

Ichitarou, the sickly heir to a large apothecary in the Edo period, has spent most of his life confined to his room because of his weak constitution. Rumors about his condition spread unpleasantly around him, so his grandfather prays for spirits to protect the boy. In response, two guardians—Sasuke and Nikichi—are sent to watch over Ichitarou for his entire life and preserve his health. As Ichitarou grows older, he starts leaving his room more often, wanting to be useful despite others urging him to rest. One day, he slips out alone without his guardians and remains outside until dark. On his way home, a bleeding man suddenly chases him. Ichitarou manages to escape using his quick thinking and stumbles upon the scene of a brutal murder. The next day, he hears about the killing, but the story seems strange—the victim's fatal wound differs from what Ichitarou witnessed. With the murderer still at large, Ichitarou begins gathering more details about the peculiar case from both humans and spirits, and these clues may help him solve the mystery.

While assisting at an anime convention to promote his city, high school student Kakeru Niimi is caught in a sudden earthquake. Amid the chaos, he enters a shrine and sees a peculiar relic shatter. The next day, his classmate Miyako Kujou, who was cosplaying at the event, worries that she has been cursed because of the earthquake, but Niimi dismisses her concerns. His perspective changes when he discovers that numerous people in the city have gained supernatural powers—and that some have already begun using them for malicious purposes. Fortunately, Niimi is not by himself: he is joined by Miyako, his sister Sora, and a cold girl named Noa Yuuki, all of whom have awakened to their own abilities. To keep their hometown safe, the group must strive to prevent further incidents while uncovering the mystery behind everything.

The Hana Ningyou Project aims to manufacture the ideal idol by inserting a unique flower seed into a host body. This series chronicles the journey of young men who devote their existence to this endeavor.

Second season of Kankin Kuiki Level X.

The "authentic mystery" story follows Tomanto and friends as they solve mysteries using vegetable and fruit trivia.

Ninth season of Oshiri Tantei.