Patricia and Isabel O'Sullivan arrive at St. Claire, a college for girls, to study and live in their new home. There, they meet Alison, Wella, Catherine, and Doris, who also reside at St. Claire, and join them in team spirit. Together, the girls play games and enjoy themselves for a long time, living in harmony until Winfred appears—a sulky, rude, and antisocial girl who will not hesitate to cause all sorts of trouble for the O'Sullivan twins and their friends.